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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2B1
All Species:
40.91
Human Site:
S508
Identified Species:
90
UniProt:
P63010
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63010
NP_001025177.1
937
104553
S508
E
L
V
Q
Q
V
L
S
L
A
T
Q
D
S
D
Chimpanzee
Pan troglodytes
XP_001174136
940
104904
S508
E
L
V
Q
Q
V
L
S
L
A
T
Q
D
S
D
Rhesus Macaque
Macaca mulatta
XP_001105809
939
103490
S508
E
L
V
Q
Q
V
L
S
L
A
T
Q
D
S
D
Dog
Lupus familis
XP_867819
948
105775
S519
E
L
V
Q
Q
V
L
S
L
A
T
Q
D
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBG3
937
104564
S508
E
L
V
Q
Q
V
L
S
L
A
T
Q
D
S
D
Rat
Rattus norvegicus
P62944
937
104534
S508
E
L
V
Q
Q
V
L
S
L
A
T
Q
D
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521247
904
100060
S495
E
L
V
Q
Q
V
L
S
L
A
T
Q
D
S
D
Chicken
Gallus gallus
XP_415772
951
105633
S508
E
L
V
Q
Q
V
L
S
L
A
T
Q
D
S
D
Frog
Xenopus laevis
NP_001080473
951
105601
S508
E
L
V
Q
Q
V
L
S
L
A
T
Q
D
S
D
Zebra Danio
Brachydanio rerio
NP_956213
951
105606
S508
E
L
V
Q
Q
V
L
S
L
A
T
Q
D
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36000
726
81850
K339
E
L
R
I
F
Y
V
K
F
N
D
P
L
Y
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
84
98.7
N.A.
99.8
100
N.A.
90.8
97.4
95.2
93.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
92.4
98.8
N.A.
99.8
100
N.A.
92.5
98.2
96.8
95.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
91
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
91
0
91
% D
% Glu:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
100
0
0
0
0
91
0
91
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
91
91
0
0
0
0
0
0
91
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
91
0
0
0
0
0
91
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
91
0
0
0
0
% T
% Val:
0
0
91
0
0
91
10
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _